1.4 Combining Forms


Combining forms are the combination of the root and the combining vowel. The root gives the essential meaning of the medical term. The combining vowel is usually an o but occasionally an i.

The following tables go through some of the most common combining forms, their meaning, and an example of a medical term that uses the combining form. Illustrations, key concept textboxes, and review questions are included to help you better understand the combining forms. It is very important that you become familiar with all of them. Making flashcards and reviewing them daily is very important when learning a new language.

 

Table 1.1. Combining Forms   

COMBINING FORM MEANING EXAMPLE OF USE IN MEDICAL TERMS
abdomin/o abdomen abdominal
aden/o gland adenoma
amni/o amnion sac amniocentesis
an/o anus anal
append/o appendix appendectomy
angi/o vessel angiogram
arteri/o artery arteriosclerosis 
ather/o plaque atherosclerosis
arthr/o joint arthritis
axill/o armpit axillary
bi/o life biology
bronch/o bronchial tube bronchitis
bronchi/o bronchial tube bronchiectasis
carcin/o cancer carcinoma
cardi/o heart cardiology
carp/o wrist carpals
cephal/o head cephalic
cerebr/o cerebrum cerebrovascular accident

 

normal knee and knee with osteoarthritis
Fig. 1.1

Key Concept

Fig. 1.1 is an image of a normal knee and a knee that has osteoarthritis. If you break this term apart, it means “inflammation” (-itis) of the “bone” (oste/o) and “joint” (arthr/o). Note that the combining vowel is dropped because the suffix starts with a vowel.

 

picture of the lobes of the cerebrum
Fig. 1.2

Key Concept

Fig. 1.2 identifies the lobes of the cerebrum. If you break down this term, it means a “structure” (-um) surrounding the “cerebrum” (cerebr/o). Note that you drop the combining vowel because the suffix begins with a vowel.

 

Exercises

 

Table 1.2. Combining Forms

COMBINING FORM MEANING EXAMPLE OF USE IN MEDICAL TERMS
chem/o drug chemotherapy
cholecyst/o gallbladder cholecystectomy
chron/o time chronic
col/o colon colitis
cost/o ribs intercostal
crani/o skull craniotomy
cry/o cold cryotherapy
cutane/o skin cutaneous
cyst/o urinary bladder, sac with fluid cystoscope
cyt/o cell cytology
derm/o skin dermal
dermat/o skin dermatology
dur/o dura mater epidural
electr/o electricity electrocardiogram
encephal/o brain electroencephalogram
enter/o intestine (usually small) enteritis
erythr/o red erythrocyte
esophag/o esophagus esophageal

 

Fig. 1.3
different types of blood cells.
Fig. 1.4

 

 

 

 

 

 

 

 

 

 

Key Concept

An electroencephalogram (EEG) is a common diagnostic test that looks at the electrical activity of the brain. This term means “to record” (-gram) “electricity” (electr/o) in the “brain” (encephal/o). Fig. 1.3 shows a patient getting an electroencephalogram.

Fig. 1.4 is an image of several different types of blood cells. The larger disc-shaped ones are erythrocytes (red blood cells), the round, fuzzy cells are leukocytes (white blood cells), and the tiny disc-shaped cells are thrombocytes (platelets). The term erythrocyte comes from the suffix -cyte, meaning “cell,” and the combining form erythr/o, meaning “red.” Literally, it means “cell that is red” or, more commonly, “red blood cell.”

 

Exercises

 

Table 1.3. Combining Forms

COMBINING FORM MEANING EXAMPLE OF USE IN MEDICAL TERMS
gastr/o stomach gastralgia 
glyc/o sugar hyperglycemia
gnos/o knowledge diagnosis
gynec/o women, female gynecology
hem/o blood hemoglobin
hemat/o blood hematology 
hepat/o liver hepatitis
hyster/o uterus hysterectomy
inguin/o groin inguinal
isch/o to hold back ischemia
lapar/o abdomen laparotomy
laryng/o voice box laryngitis 
later/o side lateral
leuk/o white leukocyte

 

laparotomy
Fig. 1.5

Key Concept

A laparotomy scar is shown above in Fig. 1.5. This term means “to cut” (-tomy) into the “abdomen” (lapar/o).

 

Exercises

Table 1.4. Combining Forms

COMBINING FORM MEANING EXAMPLE OF USE IN MEDICAL TERMS
mamm/o breast mammography
mast/o breast mastectomy
men/o menses menorrhea
mening/o meninges meningitis
my/o muscle myalgia
myel/o spinal cord, bone marrow myeloma
nat/i birth neonatal
necr/o death necrosis
nephr/o kidney nephritis
neur/o nerve neuralgia
onc/o tumour oncology
oophor/o ovary oophorectomy
ophthalm/o eye ophthalmoscopy
oste/o bone osteoarthritis
ot/o ear otalgia

 

opthalmoscope
Fig. 1.6

Key Concept

Fig. 1.6 is an image of an ophthalmoscope, an instrument used to view and assess the eye. The term means an “instrument” (­scope) to view the “eye” (ophthalm/o). In this term, you keep the combining vowel because the suffix starts with a consonant.

Also, notice the combining form nat/i, meaning “birth,” in the table above. It is one of the few combining forms where the vowel is an i, not an o.

Exercises

 

Table 1.5. Combining Forms

COMBINING FORM MEANING EXAMPLE OF USE IN MEDICAL TERMS
path/o disease pathology
pelv/o pelvis pelvic
peritone/o peritoneum peritoneal
phleb/o vein phlebitis 
plas/o formation, growth, development neoplastic 
pneumon/o lung pneumonitis 
psych/o mind psychosis
pulmon/o lung pulmonary
radi/o X-ray radiotherapy
ren/o kidney renal
rhin/o nose rhinorrhea
salping/o fallopian tube salpingectomy
sarc/o flesh sarcoma
scapul/o shoulder blade subscapular
septic/o infection septicemia
son/o sound ultrasonography
thorac/o chest thoracic 

 

Key Concept

Septicemia means “blood infection,” or literally “blood condition,” from the suffix -emia, and the combining form septic/o, which means “infection.” Septicemia is one of the most serious infections you might see in patients. Depending on when it is identified and the type of infection, the mortality rate can be up to 50% (John Hopkins Medicine, 2022a).

 

ultrasound
Fig. 1.7

Key Concept

Fig. 1.7 is an image of a fetus created using ultrasonography. An ultrasound can be completed on many locations of the body for diagnostic purposes. The term ultrasonography means “process of recording” (-graphy) “beyond” (ultra-) “sound” (son/o).

 

Exercises

 

 

Table 1.6. Combining Forms

COMBINING FORM MEANING EXAMPLE OF USE IN MEDICAL TERMS
thyroid/o thyroid gland hyperthyroidism
tonsill/o tonsil tonsillitis
top/o to put, to place, to position ectopic
thromb/o clotting thrombocyte
trache/o windpipe (trachea) tracheotomy
ur/o urine or urea, urinary tract uremia
urethr/o urethra urethritis
uter/o uterus intrauterine
vascul/o blood vessel vascular
ven/o vein intravenous

 

Key Concept

The combining form ur/o means “urine” or “urea.” In the term uremia, ur/o means “urea.” This term means “blood condition” (-emia) with “urea” (ur-). Urea is a waste product in blood that builds up when the kidneys are not functioning properly (Betts et al., 2013).

The term uremia often gets confused with the term hematuria; however, hematuria means “a condition of urine” (-uria) with “blood” (hemat-) (Ansorge, 2022).

 

tonsillitis
Fig. 1.8
tracheostomy
Fig. 1.9

 

 

 

 

 

 

 

 

 

Key Concepts

Fig. 1.8 is an image of inflamed tonsils, or tonsillitis. This term means “inflammation” (-itis) of the “tonsils” (tonsill/o).

Fig. 1.9 is an image of a tracheostomy. This term means an “opening” (-stomy) into the “trachea” (trache/o). There are a number of medical conditions that require a patient to have a tracheostomy, including major burns, long-term comas, and certain types of tumours (John Hopkins Medicine, 2022b).

 

Exercises

 

Attribution

Unless otherwise indicated, material on this page has been adapted from the following resource:

Carter, K., & Rutherford, M. (2020). Building a medical terminology foundation. eCampusOntario. https://ecampusontario.pressbooks.pub/medicalterminology/ licensed under CC BY 4.0

 

References

Ansorge, R. (2022). Blood in urine (hematuria). WebMD. https://www.webmd.com/digestive-disorders/blood-in-urine-causes

Betts, J. G., Young, K. A., Wise, J. A., Johnson, E., Poe, B., Kruse, D. H., Korol, O., Johnson, J. E., Womble, M., & DeSaix, P. (2013). Anatomy and physiology. OpenStax. https://openstax.org/details/books/anatomy-and-physiology licensed under CC BY 4.0.

John Hopkins Medicine. (2022a). Septicemia. https://www.hopkinsmedicine.org/health/conditions-and-diseases/septicemia#:~:text=Septicemia%2C%20or%20sepsis%2C%20is%20the,the%20type%20of%20organism%20involved

John Hopkins Medicine. (2022b). Tracheostomy service. https://www.hopkinsmedicine.org/tracheostomy/about/reasons.html#:~:text=A%20tracheostomy%20is%20usually%20done,deliver%20oxygen%20to%20the%20lungs

 

Image Credits
(Images are listed in order of appearance)

Osteoarthritis by BruceBlaus, CC BY-SA 4.0

Cerebrum lobes by CSSKG, CC BY-SA 4.0

EEG cap by Thuglas, Public domain

SEM_blood_cells by Bruce Wetzel, Public domain

Exploratory Laparotomy Scar by jessica raphaela, CC BY-SA 2.0

Ophthalmoscope by Joyce Tiu, CC BY-SA 4.0

2003-10-22 Echo Tweeling-01 by DESIDERIUS, Public domain

Tonsillitis by Michaelbladon, Public domain

Tracheostomy NIH by National Heart, Lung, and Blood Institute (NHLBI), Public domain

 

 

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The Language of Medical Terminology Copyright © 2022 by Lisa Sturdy and Susanne Erickson is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, except where otherwise noted.

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